How are proteins translocated across organellar membranes?

Congenital mutations in RPS19 and other genes encoding ribosomal proteins cause Diamond-Blackfan anemia, a disorder characterized by hypoplastic, macrocytic ... Sep 28, 2006 ... However, Sec61 has a high affinity for nontranslating ribosomes and it is largely occupied in vivo. We addressed how RNC-SRP complexes can ... Feb 19, 2015 ... When ribosomes encounter consecutive AAA codons they undergo an unusual 'sliding' movement and are unable to accurately produce proteins. There are now hundreds of structures of entire ribosomes in the PDB, revealing the atomic details of many important steps in protein synthesis. Apr 9, 2025 ... RIBOSOME translate: ribosome. Learn more in the Cambridge English-Vietnamese Dictionary. Sep 19, 2022 ... The ribosome is an organelle cell, that is composed of protein and RNA, which helps in the conversion of genetic code into chains of amino acids ... Apr 24, 2020 ... In this review, we discuss ribosome heterogeneity that arises from multiple features of rRNAs, including rRNA variants and rRNA modifications, and ribosomal ... Ribosome ... Ribosomes (/ˈraɪbəzoʊm, -soʊm/) are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA ... Aug 5, 2009 ... ribosomes. At a later stage, these initial RNA genes underwent optimization to produce more defined, relatively stable pockets, and when the ... Jan 31, 2025 ... The researchers discovered that ribosomes help each other when encountering difficulties, a process they refer to as 'ribosome cooperativity'.