How do germ cells navigate the complex environment of the developing gonad?

In this article, we describe various salvage strategies that are used in the management of patients with relapsed germ cell tumors. Germ line refers to the sex cells (eggs and sperm) that sexually reproducing organisms use to pass on their genomes from one generation to the next. Apr 1, 2009 ... A fertilised egg is potentially immortal since it develops into a new organism that, in turn, can give rise to an endless series of generations. Biopsy. A doctor may recommend performing a biopsy to determine the type of germ cell tumor in the body. This is done by removing tissue or fluid from the tumor ... Nov 30, 2020 ... Primordial germ cells (PGCs) are germline competent cells which form the functional gametes of the animal. The potential usage of avian PGCs ... May 17, 1990 ... We observed 16 cases of hematologic neoplasia associated with mediastinal germ-cell tumors. twenty-eight similar cases have been reported in the literature. Aug 9, 2023 ... ... germ cell tumors, suggested that Ethan might benefit from a stem cell transplant. In this procedure, healthy stem cells are infused into a ... Researchers in the Regenerative Neurosurgery and Neuro-Oncology Lab are exploring why marrow-derived cell lines form tumors after transplantation. Most germ cell tumors are treated with chemotherapy along with radiation therapy. Chemotherapy Treatment Radiation therapy Surgery Tumors that start in specialized cells called germ cells. Symptoms include a lump, swelling, and/or pain in the affected body part, difficulty breathing, cough.