How do germ cells maintain their totipotency or pluripotency?

Germ cells are highly specialized cells with the unique ability of forming a new organism. This critical cell lineage is established very early on ... Germ cell tumors that develop in the brain or spinal cord are also called CNS (central nervous system) germ cell tumors. Benign extragonadal germ cell tumors are called benign teratomas. These tumors are usually diagnosed with imaging such as CT scans combined with blood tests but ... Jun 3, 2024 ... Germ cell exfoliation has been described as a predominant finding following administration of phthalate esters and microtubule inhibitors such as colchicine ... Feb 3, 2025 ... Patients with testicular GCT have a 5-year survival rate of 99%, 92%, and 85% for stages I, II, and III, respectively. Prompt diagnosis and ... Medline ® Abstract for Reference 4 of 'Intracranial germ cell tumors'. 4: Central Nervous System Tumours, 5th ed, WHO Classification of Tumours Editorial ... Germinomas. Germinomas are malignant germ cell tumors. Germinomas are also termed dysgerminoma when located in the ovaries; and seminoma when located in the ... Germ cells are the only cell type to give rise to the next generation in most animals. Despite this important function, how germ cell development is ... Provides guidance on controversial issues surrounding the diagnosis, treatment and follow-up of early- and late-stage testicular cancer. Houston Methodist germ cell brain tumor experts provide comprehensive diagnosis and treatment, backed by innovative research.