How do endocrine disruptors affect germ cells?

Primordial germ cells in the mouse. Extragonadal germ cell tumors have a variable clinical course, with the potential for aggressive behavior and widespread metastases. The imaging characteristics ... Dec 17, 2024 ... AFP, β-hCG, or both are elevated in approximately 85% of extragonadal nonseminomatous germ cell tumors. Small increases in serum β-hCG can be ... The Malignant Germ Cell International Consortium brings together the world's leading experts in germ cell tumors, from across the spectrum of cancer research. ... germ-cell tumors (NSGCT) treated from 1998 to 2001. The authors concluded that oxaliplatin is an active agent and that it should be evaluated in combination ... Mar 1, 2025 ... A group of germ cells grows in a way that's not normal. A tumor forms. This usually happens in an ovary or testicle. Additionally, the Department of Animal Biology houses the Penn Vet Center for Animal Transgenesis and Germ Cell Research, which enables the genetic manipulation ... Apr 11, 2018 ... Most types and stages of germ cell cancers of the ovary are treated the same way, with surgery and chemotherapy (chemo). Germ cell tumors that develop in the brain or spinal cord are also called CNS (central nervous system) germ cell tumors. Oct 1, 2021 ... Spermatocytic Tumors. A spermatocytic tumor is a rare TGCT (ie, it represents only 1% of testicular cancers) that is derived from mature germ ...