What are the potential therapeutic targets within these complex neurobiological pathways for treating alcohol use disorder and its neurological consequences?

"Alcohol is an indirect GABA agonist," says Koob. GABA is the major inhibitory neurotransmitter in the brain, and GABA-like drugs are used to suppress spasms. The pattern of damage appears to be somewhat different and species-specific in animal models of alcohol toxicity. Pathological changes that have been found to ... Mar 17, 2025 ... Cognitive effects of alcohol use may include memory loss, problems with learning, dementia, and severely hindered mental functioning in most ... Jun 13, 2023 ... Alcohol consumption has long been a prevalent aspect of social culture. Contrary to popular belief, alcohol does not directly kill brain cells. When alcohol is consumed it interacts with several neurotransmitter systems in the brain, including the inhibitory neurotransmitter GABA, glutamate, and others ... Dec 27, 2022 ... Does the proposed Brain Tissue Resource Center for Alcohol Research address the needs of the research resource that it will coordinate? Is the ... How long do the effects last? Are there any effective treatments? How does alcohol affect the brain and the rest of the body? Alcohol adversely affects the ... Alcohol Withdrawal Is an Oxidative Stress Challenge for the Brain: Does It Pave the Way toward Severe Alcohol-Related Cognitive Impairment? by. Virgile ... Alcohol does not go into fat cells as easily as other cells, so more alcohol ... Even small amounts of alcohol affect one's brain and the ability to drive. Alcohol-related brain damage (ARBD), or alcohol-related brain injury (ARBI), is an umbrella term for the damage that can happen to the brain as a result of ...