What are the key cytokines produced by inflammasome activation in rheumatoid arthritis?

... rheumatoid arthritis (RA). Principal investigator Beatriz Hanaoka, MD, a ... Getting to the root cause of impairment. To test her hypothesis, Dr ... The exact cause of RA is unknown, but it is believed to result from a combination of genetic, environmental, and hormonal factors: Genetics: Certain genetic ... Factors that increase your likelihood of developing rheumatoid arthritis include: age (it's most likely to develop between the ages of 25 and 45); gender (three ... The exact cause of rheumatoid arthritis is unknown. Researchers think it's caused by a combination of genetics, hormones and environmental factors. Normally, ... Jul 2, 2024 ... RA is an autoimmune disorder where the immune system attacks healthy body tissues, causing inflammation and damage to the joints and sometimes ... Autoimmune diseases, like rheumatoid arthritis or RA, often include challenging symptoms such as pain, swelling, fatigue, and disability. At their root, one ... Oct 28, 2024 ... RA is a complex disease that involves the intricate immune system. “We don't know how to inhibit the root cause,” Dr. Jonsson says, explaining ... Nov 1, 2022 ... Causes of Rheumatoid Arthritis · Genes. Certain genes that affect how the immune system works may lead to rheumatoid arthritis. · Environment. Jun 17, 2016 ... Rheumatoid arthritis symptoms are caused by the loss of cartilage in joints, inflamed tissue surrounding joints and a tightening gap between ... Apr 27, 2018 ... RA primarily affects the lining of the synovial joints and can cause progressive disability, premature death, and socioeconomic burdens. The ...