How do post-translational modifications of proteins contribute to autoimmunity in rheumatoid arthritis?

It can be caused by a variety of conditions, including those associated with RA, such as spondylolisthesis. To relieve sciatica, the underlying cause(s) must be ... ... underlying infection. The synovial fluid in RA will also reveal low C3 and C4 levels despite elevated serum levels.[81]. With advanced disease, joint ... Feb 4, 2019 ... Whereas osteoarthritis is attributable to age-related wear and tear, rheumatoid arthritis results from a chronic attack on the synovia by cells ... Apr 9, 2025 ... Rheumatoid arthritis is an ongoing, called chronic, condition that causes pain, swelling and irritation, called inflammation, in the joints. Oct 28, 2024 ... RA is a complex disease that involves the intricate immune system. “We don't know how to inhibit the root cause,” Dr. Jonsson says, explaining ... Your The Woodlands Sports Medicine Centre physician conducts several tests to determine the root cause of your painful joints. If you do have RA, our team has a ... Aug 14, 2017 ... Researchers single out a particular immune cell that may be responsible for chronic inflammation in RA, at least in part. Nov 1, 2022 ... Causes of Rheumatoid Arthritis · Genes. Certain genes that affect how the immune system works may lead to rheumatoid arthritis. · Environment. FM and RA are both chronic conditions that affect the musculoskeletal system. And both can cause pain, fatigue, sleep disturbances and mood challenges. Aug 22, 2024 ... Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily attacks the joints, causing inflammation, pain, stiffness, and swelling ...