What is the history of statin development?

... benefits of reducing LDL-C below 100 mg/dl. TABLE 1. www.frontiersin.org ... Atorvastatin, 10 mg; simvastatin, 20 mg; fluvastatin, 80 mg; and lovastatin ... Most patients are prescribed simvastatin at dosages of 10, 20, or 40 mg/day. However, the use of simvastatin at 80 mg/day is restricted because of a high ... Jul 24, 2024 ... Zocor (simvastatin) is a prescription drug that treats high cholesterol and other conditions. Learn about side effects, dosage, uses, ... 20 mg. 90 ct. Simvastatin Tablets. Accord NDC16729-005-15. Brand NameZocor ... Terms of Use · Privacy Policy · California Privacy Policy · CCPA Authorized Agent ... Dec 20, 2023 ... One DDD of simvastatin is equivalent to 30 mg of simvastatin or 20 mg of atorvastatin. Medication use. Medication use with their ... May 14, 2024 ... Simvastatin 40 mg tablets switched to atorvastatin due to amiodarone · Simvastatin dose reduced to 20 mg od as prescribed concomitant amiodarone ... Jul 8, 2024 ... Simvastatin is commonly used to lower bad cholesterol levels (LDL-C) and fats (triglycerides) in the blood. It also increases good cholesterol levels (HDL). Oct 14, 2024 ... For moderate-intensity therapy, atorvastatin 10 to 20 mg, rosuvastatin 5 to. 10 mg, or pravastatin 40 to 80 mg can be used. If a low-intensity ... Feb 21, 2025 ... Cost-Effectiveness Analysis of Statins, Berberine, and Their Combined Use ... The intervention strategies of no intervention, atorvastatin 20 mg ... Atorvastatin increased geometric mean fibrinogen by 12–20% vs. a 0–6% fall with simvastatin (p≪0.001). Side effects were noted in 10–36% of patients, including ...