Is simvastatin safe for long-term use?

Simvastatin is used along with a proper diet to help lower bad cholesterol and fats (such as LDL, Triglycerides) and raise good cholesterol (HDL) in the blood. Simvastatin. Drug Classes. Lipid-lowering agents. Formulation. Oral - Solid: 5 mg; 10 mg; 20 mg; 40 mg. Indication. (1) Mixed hyperlipidaemia; (2) Coronary ... The aim of this study was to determine whether simvastatin 20 and 40 mg/d have an effect on systolic and diastolic blood pressure (SBP and DBP, respectively) Jul 8, 2024 ... Simvastatin is commonly used to lower bad cholesterol levels (LDL-C) and fats (triglycerides) in the blood. It also increases good cholesterol levels (HDL). Apr 13, 2023 ... When used with amlodipine, the maximum dose of simvastatin is now 20mg; higher doses are 'off-label'. For patients taking amlodipine and ... Feb 2, 2016 ... We've been prescribing statins since the 1990s for patients at high risk for stroke and heart disease. With statins, the side effects actually ... ... simvastatin 20 mg and simvastatin 40 mg alone. The mean percentage change in ... Cookies are used by this site. Cookie Settings. All content on this ... weighed against the risks of these combinations. ‡. The combined use of simvastatin at doses higher than 20 mg daily with amiodarone or verapamil should be. Nov 4, 2010 ... However, despite the substantial lipid-lowering associated with the use of statins, LDL-C reductions beyond that achieved by currently used ... Aug 21, 2017 ... ... 20 mg/kg/day. Xu et al. administered simvastatin locally (0.8mg/0.05mL), orally (25 mg/Kg/day) and used both administration routes in a ...