How can we ensure that the development of new medications addresses the most pressing public health needs?

Statin-associated side effects. J Am Coll Cardiol. 2016;67(20):2395-2410. Ganga HV, Slim HB, Thompson PD. A systematic ... ... mg/d, and pravastatin 40 mg/d). All the participants gave written informed ... 17-20 Statins are the leading therapeutic class of lipid-lowering agents ... Aug 26, 2024 ... You may need to take simvastatin on a long-term basis for the treatment of high cholesterol. You may need to stop using this medicine for a ... May 15, 2024 ... Statins can reduce that risk by lowering cholesterol. Statins may raise blood sugar, but the benefits for many outweigh that risk. medicine and ... (n [ 739), 20 mg or less (n [ 920), or more than 20 mg. (n [ 1,284) ... that statins can be used for primary prevention of acute cardiovascular events ... Mar 22, 2024 ... We suggest that atorvastatin 20 mg daily can be used as an alternative statin. (Grade 2B). • We suggest that people on a low-intensity statin ... Dec 11, 2014 ... ... simvastatin 80 mg did not provide any significant benefits over simvastatin 20 mg. The incidence of MVEs was similar for 80 mg (1477, 24·5 ... Dec 11, 2014 ... Use of amlodipine 5 mg with simvastatin 5 mg ... mg plus amlodipine, compared with 20 reports with simvastatin 20 mg plus amlodopine. Jul 27, 2017 ... The following measures can be used to assess the quality of care or service provision specified in the statement. ... 20 mg. For example, this may ... Participants prescribed a non-study statin by their own doctor had the study simvastatin tablets stopped. To assess the effects of the simvastatin allocation on ...