What is the significance of a low GFR value?

Sep 23, 2007 ... A final hydrodynamic diameter <5.5 nm resulted in rapid and efficient urinary excretion and elimination of quantum dots from the body. This ... Kidney (renal) failure is when kidneys don't work as well as they should, to the point where kidney replacement is required. Feb 13, 1975 ... The clearance ratio is abnormally high only in acute pancreatitis, and suggests that this phenomenon is due to an effect on the kidney rather than to different ... Mar 11, 2019 ... Abstract. Augmented renal clearance (ARC) is a phenomenon in critically ill patients characterized by increased creatinine clearance and ... The route of elimination requires further study. The drug appears to undergo metabolism. Excretion of unchanged drug and metabolites is via the kidneys. The ... Since the plasma creatinine level does not stand out, a normal renal function is presumed, and the doses of renal-clearance drugs are titrated consequently. The ... In conclusion, ionization state, lipophilicity, and polar descriptors are found to be the physicochemical determinants of renal clearance. These fundamental ... Aug 20, 2014 ... Opioids in renal failure and dialysis patients. J Pain Symptom Manage. 2004;28:497-504. 10. Smith H, Bruckenthal P. Implications of opioid ... We have precisely defined the requirements for renal filtration and urinary excretion of inorganic, metal-containing nanoparticles. Mar 2, 2023 ... We determined levels of emerging and legacy PFAS in human milk and urine samples from Chinese breastfed infants, estimated renal clearance, and predicted ...