What are the research priorities in the field of kidney disease and renal clearance for the next decade?

Sep 7, 2017 ... Cockcroft and Gault equation utilizing the adjusted body weight to calculate an estimated creatinine clearance ... Estimated IBW: Males: IBW = 50 ... Drug elimination is usually divided into two major components: excretion and biotransformation. Drug excretion is the removal of the intact drug. Nonvolatile ... Renal clearance is the rate at which certain substances are removed from the plasma by the kidneys. It helps to measure how well the kidneys are filtering ... Feb 5, 2019 ... Augmented renal clearance is associated with suboptimal exposure to critical medications, including β-lactams and vancomycin, increasing the ... Oct 26, 2023 ... Augmented renal clearance (ARC) remains an underappreciated clinical condition, and strategies for managing it are still being developed. ARC ... This formula is applicable only if the serum creatinine is stable. Est. Creatinine Clearance = [[140 - age(yr)]*weight(kg)]/[72*serum Cr(mg/dL)] May 19, 2023 ... Renal failure is a risk factor for developing tuberculosis (TB). • Diminished renal clearance of drugs used to treat TB puts the patient at. In conclusion, ionization state, lipophilicity, and polar descriptors are found to be the physicochemical determinants of renal clearance. These fundamental ... For individual patients with some renal dysfunction, the GFR is often determined from the creatinine clearance. Creatinine is eliminated only by glomerular ... Nov 1, 1972 ... Renal Clearance and Brain Tumor Localization in Mice of 99mTc Compounds of (Sn)DTPA, (Iron-Ascorbic Acid) DTPA, and Iron-Ascorbic Acid.