What are the mechanisms of drug-induced nephrotoxicity related to altered renal clearance?

Creatinine Clearance calculator. The Creatinine Clearance calculator has been removed this website. Alternative calculators can be found within the followng ... Patients in whom both renal function and estriol production were subnormal characteristically exhibited normal estriol clearance: estriol excretion rates ... Renal clearance is the process by which a substance in blood is filtered in the kidneys and then excreted in the urine. Aug 20, 2023 ... Creatinine clearance test ... The creatinine clearance test helps provide information about how well the kidneys are working. The test compares ... When someone develops end-stage kidney failure, their kidneys can no longer function properly. As a result, the patient needs dialysis, which replicates what ... Examples of complications from CKD that may result in hospitalization include stroke, congestive heart failure, hypertensive crisis, or acute kidney failure ... Augmented renal clearance appears to be a common finding in this patient group, with sustained elevation of creatinine clearance throughout the first week in ... Augmented renal clearance (ARC) has been reported in children with malignancies and has been associated with subtherapeutic antibiotic concentrations. This narrative review is intended to provide a contemporary assessment of antibiotic use in ARC patients from a pharmacokinetic/pharmacodynamic (PK/PD) ... Augmented renal clearance was identified in one of 10 critically ill pediatric patients using vancomycin clearance, with an increase of approximately 50 mL/min ...