What are the effects of high doses of kratom?

Kratom is illegal to buy, sell, possess or use: · Alabama · Arkansas · Indiana · Rhode Island · Vermont · Wisconsin. Kratom is legal, but may be regulated:. Sep 28, 2022 ... Kratom can be addictive because it binds to opioid receptors in the brain, and when it wears off, users can feel depressed and anxious. As an herbal supplement, it is also said to relieve pain and help with anxiety and depression. Despite its widespread availability, this substance can be ... Kratom has been used by natives of Thailand and other regions of Southeast Asia as an herbal drug for decades. Traditionally, kratom was mostly used as a ... Mar 12, 2021 ... A person can overdose on the drug, which may cause a fast heart rate, nausea, and in some rare cases, death. Aug 21, 2023 ... Kratom (Mitragyna speciosa) is a tropical evergreen tree in the coffee family. It's native to Thailand, Myanmar, Malaysia, and other South Asian countries. Apr 1, 2025 ... (2019). Kratom Use and Toxicities in the. United States. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 39(7), 775–777 ... Sep 17, 2024 ... The active ingredient in kratom is banned in a handful of states, including Alabama, Arkansas, Indiana, Rhode Island, Vermont and Wisconsin, ... Kratom is a legal “herbal remedy” with illicit recreational drug effects. The pharmacokinetics suggest the potential for drug–drug interactions and a dose- ... Kratom tea is generally considered safe when used in moderation, there are potential negative side effects, including nausea, vomiting, dizziness, constipation ...