How does kratom interact with the opioid system?

Apr 20, 2016 ... Kratom, a tree originating from Southeast Asia, has been used for hundreds of years to treat different health conditions in socio-religious ... Feb 13, 2018 ... The plant was labeled an opioid by the US Food and Drug Administration (FDA) in February 2018. It made this determination based on a 3-D modeling study of its ... Jun 28, 2021 ... Kratom is on the rise. Between 3 and 5 million Americans use the herbal supplement, either recreationally or to self-manage medical conditions such as pain or ... Apr 3, 2020 ... Hepatotoxicity. Chronic use of kratom recreationally has been associated with rare instances of acute liver injury. The onset of injury is ... Sep 17, 2024 ... The active ingredient in kratom is banned in a handful of states, including Alabama, Arkansas, Indiana, Rhode Island, Vermont and Wisconsin, ... Sep 28, 2022 ... Kratom can be addictive because it binds to opioid receptors in the brain, and when it wears off, users can feel depressed and anxious. Sep 25, 2023 ... The active constituents in the plant have the ability to behave similarly to some of our milder opioid drugs. As a result, kratom is used by ... Sep 13, 2023 ... In Florida, Kratom has gained popularity in the last 10 years, with the substance being sold at gas stations and smoke shops all over the state, and even some ... Kratom Consumer Protection Act. SECTION 2. As used in sections 2 to 7 of this. 2022 Act: (1) “Kratom product” means a food, food product, food ingredient ... Mar 25, 2022 ... What is kratom? How does kratom affect the body? How do kratom compounds work in the brain? How is NIDA advancing research on kratom?