Can early-life gut microbiome composition predict the risk of chronic diseases later in life?

Feb 1, 2017 ... Our results describe a novel causal role of aberrant gut microbiota in contributing to the pathogenesis of hypertension. Multiple indicators of gut dysbiosis predict all-cause and cause-specific mortality in solid organ transplant recipients. Gut 2024; 73:1650-1661. doi ... May 10, 2024 ... Loss of PAT1 results in compromised gut-barrier integrity, microbial dysbiosis associated with alterations in host–microbe metabolic axis, and ... Jul 24, 2020 ... Furthermore, gut dysbiosis was recently reported in Huntington's disease transgenic mice. Our main objective was to characterize the gut ... Intestinal dysbiosis is defined as differences in ratios of bacterial groups compared with those found in healthy dogs and is often accompanied by a reduction ... The DI provides reference intervals for these bacterial groups and additionally calculates a single number that expresses the extent of intestinal dysbiosis ( ... May 4, 2023 ... This review aims to present the most important effects of long-term PPI use and provides critical insights into the role of probiotic intervention in PPI ... Common nutritional strategies for altering the intestinal microbiome include dietary modifications and administration of prebiotics, probiotics or synbiotics. Oct 22, 2021 ... Gut dysbiosis caused by an HFD results in increased permeability of the gut epithelium and higher lipopolysaccharide (LPS) translocation ... Antibiotics are widely applied for the treatment of bacterial infections, but their long-term use may lead to gut flora dysbiosis and detrimental effects on ...