What is circulating tumor DNA (ctDNA) and its potential use in Ewing sarcoma

Ewing's sarcoma is a tumor made up of cancer cells that occurs in or around bone. It is the second most common type of bone cancer in children and adolescents. Jan 30, 2017 ... Ewing sarcoma tumors are characterized by high and variable levels of intra-tumor heterogeneity ... Having investigated DNA methylation ... Apr 24, 2024 ... An Ewing sarcoma researcher at MUSC is one of three scientists nationwide to receive a career development award from the Rally Foundation. Ewing sarcoma VDC/IE (vinCRISTine, DOXOrubicin, CYCLOPHOSPHamide/ iFOSFamide, etoposide) overview EML The treatment of sarcoma is complex and combined modality ... One of the most striking recurrent events found in our sequencing effort was mutations or rearrangements of the STAG2 gene. In further support of a functional ... Osteosarcoma and Ewing's sarcoma are malignant (cancerous) tumors that begin either in the bone or in the tissue around the bone. Ewing's sarcoma that has not responded to treatment or has returned after an initial response to treatment is considered recurrent. Localized Ewing sarcoma of the bone in children is usually treated with chemotherapy first. It may then be treated with surgery or radiation therapy. Jun 1, 2016 ... There are several types of Ewing sarcoma, including Ewing sarcoma of bone, extraosseous Ewing sarcoma, peripheral primitive neuroectodermal ... Nov 17, 2023 ... Ewing's Sarcoma Overview. Ewing's sarcoma is a rare type of cancerous tumor that grows in the bones or the soft tissue around the bones, such as ...