What is the role of combination therapies in overcoming EGFR inhibitor resistance?

MDRD GFR Equation estimates GFR in CKD patients using creatinine and patient characteristics. IMPORTANT This calculator includes inputs based on race. EGFRvIII displays low-level constitutive signaling that is augmented by reduced internalization and downregulation. Aberrant EGFRvIII signaling has been shown ... Jan 19, 2015 ... eGFR takes into account the serum creatinine value and also patient ... For CT, eGFR > 45 indicates no increased risk of kidney damage from ... Mar 6, 2020 ... An EGFR mutation test may be ordered by itself or as part of a panel (a series of tests to detect mutations in other genes such as KRAS, ALK and ... Aug 14, 2023 ... EGFR is the test used to measure kidney function or to determine the stage of existing kidney disease. It is also used to monitor kidney disease ... Jun 22, 2023 ... Cystatin C is recommended for measuring estimated glomerular filtration rate (eGFR) when estimates based on creatinine (eGFR cr ) are not thought to be ... Our study provides age- and gender-specific reference values of GFR in a population of Caucasian persons without identifiable risk. The MASCC EGFR Inhibitor Skin Toxicity Tool© (MESTT) assists health providers with the monitoring and reporting of dermatologic adverse effects in patients ... tyrosine kinase inhibitors (TKI) (eg, erlotinib, gefitinib): these bind to the tyrosine kinase domain in the epidermal growth factor receptor and stop the ... Nov 13, 2021 ... This retrospective cohort study furnish the evidence that therapeutic responses and survival of untreated NSCLC population with EGFR 19delins mutation are equal