What are the ethical considerations related to the development and use of predictive biomarkers for EGFR-targeted therapy?

Mar 12, 2024 ... Is it good to have a high glomerular filtration rate? A GFR of 90 or higher is considered normal if you're healthy unless you have other ... Alongside your eGFR, urine tests can help give a more accurate picture of how well your kidneys are working. Other tests. Sometimes other tests are also used to ... Stages of CKD. Stage 1. Includes signs of mild kidney disease, with a normal GFR showing 90 percent or higher kidney function. Stage 2. EGFR-positive non small cell lung cancer (NSCLC), a mutation, or damage, in a gene causes the EGFR to remain stuck in the “on” position. The amount of waiting time a kidney patient has accrued is critical - it plays a big role in the prioritization of kidney offers. If the Black race variable was ... Sep 6, 2024 ... 9 likes, 0 comments - therenalproject on September 6, 2024: " **What is eGFR Test for Kidneys?** The eGFR (estimated glomerular ... Two tests have met the FDA criteria for EGFR genetic testing: 1. Effective 6/01/16 cobas EGFR Mutation Test is a real-time PCR test for the qualitative ... Jan 25, 2024 ... What does it mean if my eGFR is below normal? If eGFR is below normal it may be due to a true reduction of kidney function. However, it is also ... CKD stage 5 is e GFR less than 15 ml/min, established kidney failure, when dialysis or a kidney transplant may be needed. What is the treatment for CKD? There ... EGFR exon 20 insertion mutations. There are other, less common mutations. One kind of EGFR mutation is called an “exon 20 insertion” mutation. While rare, exon ...