How can we improve the efficacy of EGFR inhibitors?

Nov 10, 2022 ... Abstract ... Amivantamab, a fully human bispecific antibody targeting EGFR and MET, is approved in the United States and other countries for the ... Sep 20, 2022 ... Race-based eGFR values. Glomerular filtration rate (GFR) is a measure of how fast a person's kidneys are filtering waste and excess water from ... Mar 28, 2024 ... Kidney function tests refer to medical tests used to evaluate the functions and health of kidneys. There are several kidney function tests, usually involving ... Jan 3, 2025 ... What is eGFR? eGFR (estimated glomerular filtration rate) is a measure of how well your kidneys are working. Your eGFR is an estimated number ... What do the results mean? eGFR is reported in millilitres per minute (mL/min) and is written as “mL/min/1.73m2”. The “1.73m2” relates to body surface area. A ... Jan 31, 2023 ... 15% of European non-small cell lung cancer have a mutation in the EGFR gene. This is known as EGFR mutated or EGFR positive lung cancer. FARXIGA is not recommended for use to improve glycemic control in patients with type 2 diabetes mellitus with an eGFR less than 45 mL/min/1.73 m2. FARXIGA is ... Jan 19, 2015 ... eGFR takes into account the serum creatinine value and also patient ... For CT, eGFR > 45 indicates no increased risk of kidney damage from ... Acneiform rash, consisting of papules and pustules affecting the face and upper body, is the most common cutaneous reaction with epidermal growth factor ... Nov 2, 2024 ... Summary. EGFR-positive lung cancer is a type of lung cancer with a mutation in the epidermal growth factor receptor. This mutation causes the ...