How can we foster innovation and accelerate the translation of basic research findings into clinical practice?

Jun 18, 2013 ... Abstract. The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene ... Oct 22, 2021 ... eGFR is used to estimate kidney function and help diagnose and treat kidney disease. Currently, determining eGFR uses a race modifier based on whether or not ... Our study provides age- and gender-specific reference values of GFR in a population of Caucasian persons without identifiable risk. Feb 13, 2020 ... The presence of EGFR mutations in advanced lung adenocarcinoma can predict a good prognosis; E19 dels prospect to have a better prognosis than other mutations. Jan 28, 2025 ... EGFR inhibitors that target cells with either an exon 19 or exon 21 mutation: Drugs such afatinib (Gilotrif), erlotinib (Tarceva), dacomitinib ( ... The standard way to estimate GFR is with a simple blood test that measures your creatinine levels. Creatinine is a waste product that comes from the digestion ... Dec 20, 2021 ... The glomerular filtration rate, or GFR, measures how well your kidneys clean your blood. However, it's not just about getting rid of waste and extra water. Summary. EGFR mutation in lung cancer occurs due to a mutation in a person's EGFR protein. There are various subtypes of EGFR mutations. The type of EGFR ... Jun 24, 2024 ... The eGFR blood test will indicate how well the kidneys are functioning by measuring the kidneys' ability to filter toxins or waste from your ... A cohort of 346 lung cancers was tested with a commercial kit for EGFR mutations; nine of the cases had upward real-time amplification curves at late cycles.