How can we develop more clinically relevant preclinical models?

A major measure of kidney function is the glomerular filtration rate (GFR). The glomerular filtration rate is the flow rate of filtered fluid through the ... Mar 28, 2024 ... Kidney function tests refer to medical tests used to evaluate the functions and health of kidneys. There are several kidney function tests, usually involving ... The management of elderly people with a low eGFR: moving toward an individualized approach. Ann M O'Hare. Sep 15, 2021 ... Abstract. Epidermal growth factor receptor (EGFR) mutations typically occur in exons 18–21 and are established driver mutations in non-small ... A more precise formula to estimate glomerular filtrate rate (eGFR) from serum creatinine and other readily available clinical parameters. eGFR measures your kidneys' ability to filter toxins or waste from your blood. A very low number may indicate kidney failure, which requires dialysis or a ... Protein names · Recommended name. Epidermal growth factor receptor. Curated · EC number. EC:2.7.10.1 (UniProtKB | ENZYME | Rhea ) · Alternative names. Proto- ... Mar 1, 2024 ... The Food and Drug Administration approved amivantamab-vmjw (Rybrevant, Janssen Biotech, Inc.) with carboplatin and pemetrexed for the first-line treatment of ... An EGFR mutation is the most common mutation for which there are treatments available. These new treatments, which are called targeted therapies, work directly ... What is EGFR-positive lung cancer? EGFR (epidermal growth factor receptor) is a gene that helps cells grow and survive. But when it mutates, it can...