How do microglia and astrocytes, the resident immune cells of the brain, contribute to the inflammatory process in autoimmune encephalitis?

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Acquired peripheral nerve hyperexcitability syndromes include cramp-fasciculation syndrome, Issac syndrome, and Morvan syndrome. Symptoms of encephalitis vary according to the area of the brain affected and, in autoimmune encephalitis, depending on the associated antibody. Physical ... Nov 26, 2024 ... Inflammation in the brain and spinal cord can be caused by infections such as viruses. Encephalitis can also be autoimmune when antibodies can ... Jun 16, 2020 ... Conceptual definitions for two main diagnostic entities: (a) acute symptomatic seizures secondary to autoimmune encephalitis, and (b) autoimmune-associated ... Autoimmune encephalitis–related seizures present with acute or subacute seizures, often frequent from the onset. A history of preceding viral prodrome is common ... Our study confirms that adult-onset, high frequency focal seizures with prominent autonomic and emotional manifestations should be investigated for AE. Multiple ... The purpose of this clinical trial is to compare the effects, good or bad, of satralizumab against placebo in people with NMDAR AIE or LGI1 AIE. People who take ... ... autoimmune encephalitis in our patient. Further, a negative imaging screen for underlying neoplasms argues against an underlying paraneoplastic process in ... An autoimmune condition in which patient's immune system makes antibodies that attack different brain proteins, causing a spectrum of symptoms. First-line Therapies: · Intravenous Methylprednisolone (IVMP): 1g daily x 5 days followed by oral prednisone 1mg/kg (maximum dose 60-80mg daily with a prolonged ...
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