What are the strengths and limitations of using surrogate endpoints in double-blind studies?

Jan 22, 2021 ... The aim of this randomized, double-blind phase II/III study was to assess the efficacy of axitinib in patients with advanced G1-2 extra-pancreatic NETs. A Phase 2/3, Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Oral Ozanimod (RPC1063) ... Jan 23, 2025 ... This prospective, double-blind, test accuracy study was designed to test whether an artificial intelligence (AI)–guided software device (AutoDVT) could support ... The results suggest that in a subset of patients, physostigmine can induce a degree of cognitive improvement over 6 weeks of treatment. A RANDOMIZED, DOUBLE-BLIND STUDY TO ASSESS SERUM TRANSAMINASE ELEVATIONS AND ANTIBODY FORMATION FOLLOWING REPEAT SUBCUTANEOUS DOSING OF LMWH, UFH OR THE ... In this short-term study, romiplostim increased platelet counts in 88% of children with ITP and was well-tolerated and apparently safe. Apr 12, 2023 ... A double-blind study can be a useful research tool in psychology and other scientific areas. By keeping both the experimenters and the ... Prospective Double-blind-study of Supplementary Antibiotic-therapy for Duodenal-ulcer Associated with Campylobacter Pyloridis Infection. American Journal of ... Seizures were controlled in 89% of the episodes treated with lorazepam and in 76% treated with diazepam. The times for onset of action of the medications did ... Double-Blind Study pronounce term ... A type of clinical trial in which neither the participants nor the research team know which treatment a specific participant ...