How can innovative trial designs address the challenges of rare disease research?

The purpose of this research trial is to investigate the effects of LY3437943 (drug) compared with placebo on renal function, in participants who are ... Jun 14, 2022 ... Phase IIa, randomised, double-blind study of GSK3389404 in patients with chronic hepatitis B on stable nucleos(t)ide therapy A Phase 3, randomized, double-blind, study evaluating efficacy and safety of riliprubart versus intravenous immunoglobulin (IVIg) in participants with chronic ... May 10, 2021 ... We report the findings of a randomized, double-blind, placebo-controlled, multi-site phase 3 clinical trial (NCT03537014) to test the efficacy ... Sep 17, 2012 ... In a randomized double-blind study (n = 127), science faculty from research-intensive universities rated the application materials of a ... A Phase 2/3, Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Oral Ozanimod (RPC1063) ... May 15, 2020 ... Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis. The safety/tolerability of clopidogrel (plus aspirin) is superior to that of ticlopidine (plus aspirin) (P=0.005). The 300-mg loading dose was well tolerated. A double-blind, placebo-controlled, randomized study was performed to determine whether proglumide added to ongoing neuroleptic medication was efficacious ... Feb 21, 1980 ... Controlled Double-Blind Study of the Effect of Rifampin on Humoral and Cellular Immune Responses in Patients with Pulmonary Tuberculosis and ...