How does replication stress contribute to the formation of chromosomal rearrangements in cancer cells?

Oct 7, 2014 ... ... cells were in G0/G1 phase under physiological conditions (Fig. 1C). There were no significant differences in cell cycle status (G0/G1, S ... Dec 18, 2006 ... This suppression during S phase is apparently regulated by cell cycle position alone and occurs automatically during each cell cycle. If the ... The expression of apoptosis-related and cell cycle–related proteins in leukemia cells was analyzed through western blotting. The synergistic effect of the Aza ... Oct 25, 2011 ... ... during late mitosis and G to license replication origins for use in S phase. ... cell cycle in Chinese Hamster Ovary (CHO) cells. We find that ... The G0/G1 and G2/M curves are fit using the same process as the Watson model. The difference occurs in the fit of the S phase. The Dean-Jett model fit a second ... Mar 24, 2025 ... The cell cycle is a four-stage process in which the cell increases in size (gap 1, or G1, stage), copies its DNA (synthesis, or S, stage), prepares to divide ( ... Dec 16, 2021 ... In the G2 phase the cell is in the last phase before it officially divides. The cell in the G2 also increases in size much more and goes through ... Aug 21, 2023 ... 3: TRAIP is essential for S-phase progression during unperturbed cell cycle. ... This progression can also happen without chromosome ... Sep 25, 2019 ... 8 What happens during S phase of the cell cycle? a. The cell divides b. The cell undergoes its final preparation for division C. The cell ... May 1, 2008 ... This indicates nuclear DNA synthesis occurs during development. Mitosis and early S phase were both twofold longer in slugs as compared with ...