What is the evolutionary significance of SHBG?

In overweight and obese men, weight loss with both high protein and carbohydrate diets improve testosterone, sex hormone binding globulin and overall sexual ... ... could be explained by the difference in age. Mean SHBG levels were 25% higher (P = .15) in African Americans than in whites (197 +/- 104 vs 157 +/- 79 nmol ... Dec 14, 2022 ... If your SHBG levels are too high, it likely means that less of your total testosterone is free testosterone that's available for your tissues to ... Higher SHBG levels among carriers of the N allele have been reported ... Geometric mean SHBG (adjusted), by genotype, exp(β)* 95% CI, p-value (additive ... Sep 29, 2020 ... The binding affinity of SHBG for testosterone is high, and has been ... Finally, the cross-sectional analysis does not provide further insight ... Jun 17, 2016 ... Maximum dosing does not mean maximal effect. Furthermore, these ... Sex Hormone Binding Globulin (SHBG)**, PRN. Albumin**, PRN. Hemoglobin ... The high SHBG levels during pregnancy may serve to protect the mother from ... SHBG, whereas insulin does not. For example, anti-psoriatic drugs that ... Mean SHBG was significantly higher in the older group (p < 0.001) ... Routine SHBG testing should be considered for men suspected of T deficiency. Dec 14, 2022 ... A high SHBG level means it is likely that less free testosterone is available to your tissues than is indicated by the total testosterone test. Adjusted mean T was 7 % higher in the vegans than the omnivores, but this difference did not approach statistical significance. Unadjusted. SHBG was 35 9'0 ...