What are the challenges in translating basic research findings into clinical interventions for Down syndrome?

“It's just a matter of catching them before they cause more difficulty.” Meet Our Experts. Jun 1, 2020 ... Down syndrome is a chromosomal condition that is associated ... which causes Down syndrome. Like trisomy 21, mosaic Down syndrome is ... Mar 27, 2023 ... There is no clear cause of the genetic condition, although maternal age is a major risk factor for Down syndrome. Women who become pregnant at ... Oct 7, 2021 ... The main causes of death were pneumonia/respiratory infections (20.5%), congenital malformations of the circulatory system (11.2%), other diseases of the ... Down syndrome is the most frequent chromosomal cause of mild to moderate intellectual disability, and it occurs in all ethnic and economic groups. The degree of ... Down syndrome signs and symptoms. A child with Down syndrome might take longer than other children their age to reach certain milestones and to develop certain ... Trisomy 21– More than 90% of Down syndrome cases are caused by trisomy 21. An extra chromosome (chromosome 21) originates in the development of either the sperm ... Down syndrome is a condition that is caused by extra genetic material. It's one of the most common genetic conditions in the United States. The extra genetic ... Fetuses with Down syndrome have an extra copy of chromosome 21, resulting in 47 chromosomes total. This excess genetic material causes the physical and mental ... Down's syndrome is the commonest identifiable cause of intellectual disability, accounting for around 15-20% of the intellectually disabled population. It is ...