How do these non-coding RNAs interact with the protein-coding genes on chromosome 21 and other chromosomes?

Apr 26, 2023 ... They found that having a third copy of the gene Dyrk1a and at least three other genes was responsible for changes in development that result in ... Trisomy 21– More than 90% of Down syndrome cases are caused by trisomy 21. An extra chromosome (chromosome 21) originates in the development of either the sperm ... Nov 12, 2024 ... Down syndrome results from an unusual cell division involving chromosome 21. This unusual cell division results in an extra partial or full ... Apr 28, 2011 ... New research uncovers reasons why there is a higher infant mortality rate among infants with Down syndrome than among typically developing children. Jan 7, 2025 ... This study addresses fundamental questions surrounding otitis media effusion in Down syndrome, identifying DYRK1A as a key gene involved in the condition. Jul 6, 2006 ... Article. Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration. Dec 6, 2024 ... Down syndrome is by far the most common and best known chromosomal disorder in humans and the most common cause of intellectual disability. Jan 30, 2023 ... Cardiovascular disease is a leading cause of morbidity and mortality in individuals with Down syndrome. Congenital heart disease is the most ... Jun 6, 2017 ... Down syndrome is usually caused by three copies of chromosome 21. Chromosomal abnormalities. We know that 10 to 30 percent ... Dermatological manifestations of Down syndrome, Trisomy 21 syndrome, Complete trisomy 21 syndrome ... What causes Down syndrome? A cell division error during ...