How can we amplify the voices of individuals with Down syndrome and ensure that their perspectives are heard?

This work underlines a Pcp4-dependent ciliopathy in Down syndrome brain affecting cerebrospinal fluid flow. Down syndrome is caused by an extra chromosome, but experts are not certain why this occurs or what factors may play a role. One factor experts do know about is ... Apr 26, 2023 ... They found that having a third copy of the gene Dyrk1a and at least three other genes was responsible for changes in development that result in ... In 95% of cases there is the presence of an extra chromosome 21 in the cells, also lending the syndrome the name trisomy 21 (T21). The other causes are known as ... Summary · Down syndrome is a common genetic condition caused by an extra chromosome 21. · Every person with Down syndrome is an individual. · People with Down ... Down syndrome is usually caused by an error in cell division called “nondisjunction.” Nondisjunction results in an embryo with three copies of chromosome 21 ... Apr 20, 2023 ... The cause of Down syndrome is known to be an extra copy of chromosome 21, or trisomy 21. But because this chromosome contains more than 200 ... The main cause of hospitalization was due to pneumonia in 50% of cases, followed by acute respiratory failure in 14%. Most cases of Down syndrome are caused by trisomy 21. Occasionally, the extra chromosome #21 or a portion of it is attached to another chromosome in the egg or ... Down Syndrome (DS) refers to a genetic condition that is caused by an extra chromosome in the DNA chain on chromosome 21, referred to as Trisomy 21, ...