How can omics technologies (genomics, transcriptomics, proteomics, metabolomics) be used to gain a more comprehensive understanding of Down syndrome?

Mar 18, 2021 ... This additional chromosome, or portion of a chromosome, causes the common features of DS: delayed language; impaired long and short-term memory; ... Fetuses with Down syndrome have an extra copy of chromosome 21, resulting in 47 chromosomes total. This excess genetic material causes the physical and mental ... Due to weak muscle tone, the kneecaps of a child with Down syndrome may slip out of the groove. This instability will cause the knees to look deformed, but may ... Research and analysis Close Health topics Global Burden of Disease (GBD) study Health by location Health policy and planning Data tools and practices Understanding Down Syndrome: Symptoms and Causes ... Down Syndrome is a genetic condition where a person is born with an extra chromosome. Chromosomes are like ... Oct 27, 2023 ... Hypotonia often causes babies with Down syndrome to appear “floppy.” The poor muscle tone can and often does improve with age and physical ... Down syndrome (sometimes called Down's syndrome) is a condition in which a child is born with an extra copy of their 21st chromosome — hence its other name, ... Down syndrome, caused by meiotic separation of chromosome 21 in humans, is associated with advanced maternal age, but defining and understanding other risk ... Aug 15, 2000 ... Down syndrome (trisomy 21) is the most commonly recognized genetic cause of mental retardation. The risk of trisomy 21 is directly related ... Oct 20, 2023 ... Down syndrome is a genetic disorder caused by an extra full or partial cell division of a human's chromosome 21, resulting in lifelong intellectual disability, ...