Are there any non-coding RNAs on chromosome 21 that play a critical role in Down syndrome?

Down syndrome is caused by an extra chromosome, but experts are not certain why this occurs or what factors may play a role. One factor experts do know about is ... Though to varying degrees, adults with Down syndrome had consistently higher risk of death from four causes of death across all ages - influenza and pneumonia, ... In 95% of cases there is the presence of an extra chromosome 21 in the cells, also lending the syndrome the name trisomy 21 (T21). The other causes are known as ... Jul 16, 2009 ... The research sheds light on the genetic underpinnings of aneuploidy, a condition marked by having an abnormal number of chromosomes. Sensory sensitivities can also cause behavioral challenges. Behavioral challenges. Has frequent tantrums, “melt-downs," or “drop and flops” (e.g., when ... Jan 30, 2023 ... Cardiovascular disease is a leading cause of morbidity and mortality in individuals with Down syndrome. Congenital heart disease is the most ... Cerebral palsy is a neurological condition that usually occurs at birth and causes physical disabilities. Down syndrome is a chromosomal abnormality that causes ... Down's syndrome is the commonest identifiable cause of intellectual disability, accounting for around 15-20% of the intellectually disabled population. It is ... Physical signs of Down syndrome · A flat nose bridge. · Slanted eyes that point upward. · A short neck. · Small ears, hands and feet. · Weak muscle tone at ... Nov 30, 2023 ... In the United States, demographic factors also affect the risk for a child to be born with Down syndrome. These factors include geographic ...