What were the key factors that led to the widespread use and subsequent resistance to sulfa drugs

All of the commonly known sulfa drugs act similarly but there is probably some difference in the degree of anticoccidial action. Tests of 45 sulfonamides showed ... Antibiotics containing chemicals called sulfonamides can trigger a reaction if you have a sulfa allergy. These antibiotics include combination drugs. ... sulfa medication.4 This case introduced the concept of sulfa cross-reactivity to the medical community. A literature search uncovered five other case ... Aug 4, 2022 ... Study shows success at disproving allergies to sulfa antibiotics. A Vanderbilt study shows that physicians can successfully identify and ... Apr 20, 2010 ... Prontosil Rubrum was the first drug to cure bacterial infections and the first of many sulfa drugs. Sulfonamide is a functional group that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs. Sulfonamides are among the most commonly reported causes of drug-induced thrombocytopenia. 1 Affected patients typically present with purpura and platelet ... Oct 19, 2016 ... Sulfonamides, or SULFA drugs, were the first chemical substances systematically used to treat and prevent bacterial infections [1, 2], but ... Dec 22, 2017 ... A sulfa allergy may be accompanied with symptoms like hives, itchy skin, or swelling in the mouth or throat. It differs from a sulfite allergy. Dec 23, 2006 ... The development of sulfa drugs really came out of the catastrophic loses of World War I, and not just combat deaths, but battlefield deaths in which bacteria ...