What are the challenges in conducting clinical trials for cholangiocarcinoma?

TUDCA (tauroursodeoxycholic acid) is a bile acid derivative that occurs naturally in the body and helps functions like digestion, cognition, and more. Like many ... Biliary diseases occur when the bile ducts and gallbladder are damaged, impairing bile production. If left untreated, liver disease can lead to cirrhosis, or ... The liver produces a fluid called bile and stores it in the gallbladder. The gallbladder releases bile into the small intestine to help digest your food. If the ... The liver remains functional during preservation, producing bile, metabolising glucose and maintaining pH, allowing the objective assessment of organ ... ... body and breaks down poisonous substances, such as alcohol and drugs. The liver also produces bile, a fluid that helps digest fats and carry away waste. The ... Oct 30, 2024 ... The second was an FXR agonist, a drug that reduces bile acid production by turning off a specific pathway in the liver. The combination of these ... Secretes enzymes for digestion and hormones regulating metabolism. Liver, Filters the blood, removing toxins. Gallbladder, Releases bile that aids in digestion. What is Biliary Atresia? Biliary atresia is a rare disease of the liver and bile ducts that occurs in infants. Jaundice (yellowing of the skin) and pale stools ... Manufactures proteins needed for various body functions, such as blood clotting. Produces bile acids needed for digestion. Detoxifies harmful products ... What is the biliary tract? Your biliary tract, which is made up of your gallbladder and bile ducts, helps with digestion by releasing bile. The gallbladder is a ...