What is the role of the p53 tumor suppressor in regulating ribosome biogenesis?

rRNA acts as a molecular scaffold, guiding the precise positioning of ribosomal proteins within the ribosome. These interactions stabilize the ribosomal ... Jan 19, 2022 ... Aging impairs the ability of ribosomes to efficiently synthesize proteins and leads to protein misfolding and aggregation, which disrupts cellular health. Sep 1, 2018 ... Some ribosomal proteins are involved in the assembly or stability of ribosomes. Others help carry out the ribosome's main function of building ... Jul 1, 2001 ... The mechanisms that underlie ribosomal synthesis, translocation and catalysis are now being unravelled, with practical implications for the design of ... ... ribosomes might have increased during their evolution from ... Half of the antibiotics in therapeutic use today are molecules that target ribosome function ... Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation). Ribosomes link amino ... Dive into the research topics of 'The function and synthesis of ribosomes'. Together they form a unique fingerprint. Ribosome Biochemistry, Genetics and ... I. It helps in manufacture of protein molecules. II. It helps in manufacture of enzymes. III. In helps in manufacture of hormones. IV. In helps in manufacture ... Eukaryotic features of the archaeal small ribosomal subunit are presented. Ribosome evolution and TI mechanisms diversity in archaeal branches are discussed. Our work reveals a potential direct role for APOBEC3A in ribosome biogenesis likely independent of its editing function. More broadly, we found an additional ...