What are the mechanisms of resistance to ribosome-targeting anticancer drugs?

Jun 2, 2016 ... Mitochondrial ribosomes (mitoribosomes) perform protein synthesis inside mitochondria, the organelles responsible for energy conversion and ... Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation). Ribosomes link amino ... Jun 2, 2016 ... Abstract. Mitochondrial ribosomes (mitoribosomes) perform protein synthesis inside mitochondria, the organelles responsible for energy ... Sep 1, 2018 ... Some ribosomal proteins are involved in the assembly or stability of ribosomes. Others help carry out the ribosome's main function of building ... Ribosomes are small cellular structures made up of proteins and ribosomal RNA (rRNA). Their primary function is to facilitate the process of protein synthesis, ... Jul 23, 2024 ... In cancer cells, RPs are produced in excess. ... Degradative ubiquitylation of ribosomes also proved to be important in the no-go decay (NGD) and ... function of ribosomes by stating that “[r]ibosomes create the proteins,” and 1 point was earned for describing the function of mitochondria: “They supply ATP. The bacterial ribosome is a cytoplasmic nucleoprotein particle whose main function is to serve as the site of mRNA translation and protein synthesis. Mar 23, 2018 ... Researchers add missing pieces to puzzle of how red blood cells develop ... For the first time, cellular machines called ribosomes, which create ... Dec 7, 2020 ... Fox dove into the structure at the center of the modern ribosome in order to uncover clues about the events that led to the formation of the ...