Can interventions that target ribosomes affect lifespan?

Jan 13, 2010 ... (PhysOrg.com) -- When ribosomes produce protein in all living cells, they do so through a chemical reaction that happens so fast that ... Dive into the research topics of 'The function and synthesis of ribosomes'. Together they form a unique fingerprint. Ribosome Biochemistry, Genetics and ... Oct 28, 2019 ... In the present study, we investigated mechanism(s) by which suppression of RPL12 rescues F508del protein synthesis and activity. Ribosomes are molecular machines that translate the genome into protein. ... Ribosome function; Stress response; Translation. Research Beacons, Institutes ... Our work reveals a potential direct role for APOBEC3A in ribosome biogenesis likely independent of its editing function. More broadly, we found an additional ... Jan 23, 2023 ... This video shows an mRNA strand moving through the ribosome as tRNA molecules carry in amino acids to build a protein according to the mRNA code. Jul 1, 2001 ... The mechanisms that underlie ribosomal synthesis, translocation and catalysis are now being unravelled, with practical implications for the design of ... Apr 21, 2024 ... Here we report the discovery of a new general translation factor that targets stalled ribosomes and promotes protein synthesis in an evolutionarily conserved ... Jan 19, 2022 ... Aging impairs the ability of ribosomes to efficiently synthesize proteins and leads to protein misfolding and aggregation, which disrupts cellular health. Ribosomes are small cellular structures made up of proteins and ribosomal RNA (rRNA). Their primary function is to facilitate the process of protein synthesis, ...