What are the potential therapeutic strategies targeting lipid metabolism to overcome drug resistance?

Jul 12, 2022 ... The importance of neuroglia in maintaining normal brain function under physiological and pathological conditions has been supported by ... Functions of Lipids · Triglycerides: Function as a long-term energy source in animals (fats) and plants (oils) · Phospholipids: Structural component of cell ... In contrast, some studies have found a time- and dose-dependent decrease in platelet aggregation with administration of IVLEs. One study revealed that high ... This study was designed to characterize lipid droplet (LD) formation in EC by manipulating pathways leading to the formation and degradation of LD. Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment. The body needs protein to maintain and replace tissues and to function and grow. Protein is not usually used for energy. However, if the body is not getting ... Fat helps the body absorb vitamin A, vitamin D and vitamin E. These vitamins are fat-soluble, which means they can only be absorbed with the help of fats. Any ... Feb 13, 2015 ... Dietary fats are not just a source of energy; they function as structural building blocks of the body, carry fat-soluble vitamins, are involved ... ApoE is produced in abundance in the brain and serves as the principal lipid transport vehicle in CSF. It is induced at high concentration in peripheral nerve ... Apr 20, 2022 ... To optimize their function or, more specifically, interaction with cell membranes, their composition often includes ionizable lipids which ...