What are the hurdles in developing new drugs that target lipid metabolism?

Apr 19, 2021 ... In comparison, the unsaturated fats help to raise HDL (good) cholesterol levels. HDL picks up excess LDL in the blood and moves it to the liver, ... ApoE is produced in abundance in the brain and serves as the principal lipid transport vehicle in CSF. It is induced at high concentration in peripheral nerve ... However, fats are essential to the body and have a number of important functions. For instance, many vitamins are fat-soluble, meaning that they must be ... Apr 12, 2012 ... ... function, blood lipids and other potential adverse effects ... Effect of increased potassium intake on blood pressure, renal function, blood ... Nov 2, 2021 ... Abstract. Lipids are essential constituents of cellular membranes. Once regarded merely as structural components, lipids have taken centre stage ... May 2, 2022 ... The effects of high-fat diet and CCl4 administration on liver function and lipid profile in non-alcoholic fatty liver disease rat model. Jan 24, 2024 ... They act as messengers, helping proteins do their jobs. They also start chemical reactions that help control growth, immune function, ... Lipid droplets have important functions beyond energy homeostasis. They store vitamins, signaling precursors, and other hydrophobic molecules. May 1, 2023 ... Fats and lipids are an essential component of the homeostatic function of the human body. Lipids contribute to some of the body's most vital ... Mar 15, 2023 ... The functional role of a biological molecule hinges on its unique structure. The context by which structure impacts function is a vital ...