How have stereocilia adapted to different acoustic environments and lifestyles?

May 10, 2021 ... We show that IHC and OHC stereocilia are similarly TM-embedded and that Ca 2+ ducts connect the TM to the stereocilia of IHCs and OHCs. For the latter option to work without downtime, each stereocilium (or sets of mechanically-connected stereocilia) must be able to execute the recovery by itself ... The stereocilia of each hair cell are arranged in a precise geometry. This arrangement is asymmetrical and polarized because the stereocilia are arranged in ... Trouble detecting soft or high-pitched sounds is often the first sign that stereocilia — the delicate hair cells that convert sound waves into electrical ... Feb 22, 2024 ... Today's #LabVocab is stereocilia – a part of the ear that plays a critical role in how humans experience sound and balance. These results suggest that regulation of stereocilia length occurs through EPS8 and that CDH23 and PCDH15 regulate stereocilia lengthening beyond their role in ... Mar 11, 2019 ... The tip links are connected to stretch-activated cation channels on the tips of the stereocilia. When a sound wave vibrates the basilar membrane ... Male Smpx null mice showed a progressive hearing loss starting from high frequency at the 3rd month. Hearing loss in female mice was milder and occurred later. Feb 28, 2021 ... 1. Cilia can be motile or non-motile, whereas stereocilia are characterized by their lack of motility. 2. Stereocilia are actually more associated with ... PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing. Nature Comm. 10: 3801. 153. György, B., Nist-Lund, C., Pan, B., Asai ...