How does CHARGE syndrome affect multiple organ systems, including hearing and balance?

... stereocilia? How did the authors explain inconsistencies with previous published results by Ohmori? c) What was the nature of the evidence that transduction ... Aug 23, 2016 ... Abstract. Stereocilia are actin-based protrusions on auditory and vestibular sensory cells that are required for hearing and balance. They ... ... stereocilia bathing in the surrounding endolymph. The cell body itself is localised in the perilymph compartment (see transverse section of the organ of ... Jun 20, 2019 ... We report that TRIOBP-5 is essential for thickening bundles of F-actin in rootlets, establishing their mature dimensions and for stiffening supporting cells. Deflection of the bundle of stereocilia is mechanically responsible for stretching ion pores in the stereocilia, allowing a cation current to pass into the cell ... They have more stereocilia and long stereocilia relative to kinocilia heights. Tip link tensions show parallel behavior in peripheral columns of the bundle ... They are distinct from cilia and microvilli, but are closely related to microvilli. They form single "finger-like" projections that may be branched, with normal ... Feb 28, 2021 ... 1. Cilia can be motile or non-motile, whereas stereocilia are characterized by their lack of motility. 2. Stereocilia are actually more associated with ... For the latter option to work without downtime, each stereocilium (or sets of mechanically-connected stereocilia) must be able to execute the recovery by itself ... the stereocilia and in the epithelial lining of the first segment of the ductus epididymidis in mice by Becker and McEnery. (1966). The function of the ...