How does Alport syndrome primarily affect the kidneys and hearing?

Play Quordle: Guess all four words in a limited number of tries. Each of. Can you solve 4 words at once? Jul 21, 2022 ... Sensorineural Hearing Loss. Inside the inner ear is the cochlea, which is lined with tiny hair cells called stereocilia that convert soundwaves ... ... stereocilia. These stereocilia are grouped into hair bundles, and the stereocilia in each hair bundle work together to facilitate the conversion of physical ... Jan 4, 2021 ... show that ADF/cofilin-1 are recruited to mechanotransducing auditory stereocilia tips, where they increase the availability of F-actin barbed. Mar 13, 2020 ... When stereocilia become damaged, they do not regenerate, and sensorineural hearing loss is the result. While there are no surgeries that can ... These results provide the first direct evidence that type I hair cells have significantly more stereocilia than type II hair cells. Jun 20, 2019 ... We report that TRIOBP-5 is essential for thickening bundles of F-actin in rootlets, establishing their mature dimensions and for stiffening supporting cells. Oct 13, 2017 ... These two models could be tested by manipulating Ca2+ or actin-depolymerizing molecules in the stereocilium and examining effects on stereocilia ... The organ of Corti contains tiny hair cells with stereocilia at the ends. Stereocilia are delicate, hair-like projections that react to cochlea fluid movement. Aug 13, 2024 ... Within the inner ear lies the cochlea, which is your organ of hearing, and it houses tiny nerve endings called stereocilia. Sensorineural ...