How are stereocilia organized within the organ of Corti?

These results suggest that regulation of stereocilia length occurs through EPS8 and that CDH23 and PCDH15 regulate stereocilia lengthening beyond their role in ... Apr 26, 2024 ... Stereocilin is associated with hairlike structures called stereocilia, which project from specialized cells called hair cells in the inner ear. When your head moves, the endolymph moves the cupula and stimulates the stereocilia. Vertigo is a feeling of dizziness or sudden sensation of spinning when ... These results provide the first direct evidence that type I hair cells have significantly more stereocilia than type II hair cells. Apr 6, 2016 ... ... stereocilia. While functionally very different, the protein complexes that organize microvilli and stereocilia have striking parallels. Both ... We previously reported that CIB2 binds to WHRN and is essential for stereocilia staircase architecture of cochlear hair cells. Here, we refine the ... Mar 13, 2020 ... When stereocilia become damaged, they do not regenerate, and sensorineural hearing loss is the result. While there are no surgeries that can ... Deflection of the bundle of stereocilia is mechanically responsible for stretching ion pores in the stereocilia, allowing a cation current to pass into the cell ... Jun 11, 2019 ... ... stereocilia. The stereocilia within the same hair bundle have differing lengths. They are aligned in an orderly way to form a wedge shape ... Mar 11, 2019 ... The tip links are connected to stretch-activated cation channels on the tips of the stereocilia. When a sound wave vibrates the basilar membrane ...