What are the novel mechanisms of antibiotic resistance being discovered in Pseudomonas aeruginosa and what are their clinical implications?

The bacteria are found widely in the environment, such as in soil, water, and plants. They usually do not cause infections in healthy people. If an infection ... Jul 5, 2024 ... A series of epidemic clones emerged and expanded between 1850 and 2000, indicating recent selective pressures, possibly driven by industrialization, associated ... Our results suggest that ExoS facilitates P. aeruginosa penetration through the intestinal epithelial barrier by binding to FXYD3 and thereby impairing the ... Jan 20, 2023 ... Pseudomonas aeruginosa is an opportunistic pathogen that requires iron for growth and virulence, yet this nutrient is sequestered by the ... Pseudomonas aeruginosa infections are the predominant driver of CF lung disease, and airway isolates are frequently resistant to multiple antimicrobials ... Pseudomonas aeruginosa is a bacteria that can be found in hot tubs and pools. Pseudomonas aeruginosa is a bacteria known commonly to cause “hot tub. May 14, 2014 ... A Pseudomonas aeruginosa type VI secretion phospholipase D effector targets both prokaryotic and eukaryotic cells. Cell Host Microbe. 2014 May ... PA does appear to be an 'egg' rather than a 'chicken' in COPD, with mounting evidence of its role in exacerbations, hospitalizations, and mortality. In this paper, we rigorously explore the role of two major bacterial adhesins, type IV pili (Tfp) and flagella, in bacterial adherence to distinct host ... Apr 11, 2024 ... Key points · Pseudomonas aeruginosa (P. aeruginosa) infections typically occur in healthcare settings. · Good hand hygiene and infection ...