How can artificial intelligence and machine learning algorithms be used to analyze large datasets and identify novel biomarkers or therapeutic targets for Pseudomonas aeruginosa infections?

Aug 9, 2017 ... Pseudomonas aeruginosa (P. aeruginosa) is a common Gram-negative, rod-shaped bacterium. It lives primarily in water, soil and vegetation. Pseudomonas aeruginosa is a free-living, aerobic and motile Gram-negative rod bacterium. It is the cause of several disorders in animals and human. Some Pseudomonas aeruginosa bacteria are resistant to carbapenem antibiotics, which are often reserved for serious infections. These are called carbapenem- ... Oct 12, 2022 ... PAO1 and PA14 are common laboratory reference strains, modeling moderately and hyper-virulent phenotypes, respectively. Multidrug efflux pumps are among the main Pseudomonas aeruginosa antibiotic-resistance determinants. Besides, efflux pumps are also involved in other ... Jan 20, 2023 ... Pseudomonas aeruginosa is an opportunistic pathogen that requires iron for growth and virulence, yet this nutrient is sequestered by the ... Antibiotics with a novel mode of action will be needed to avoid cross resistance against currently used therapeutic agents. Importantly, antivirulence drugs are ... Jul 5, 2024 ... A series of epidemic clones emerged and expanded between 1850 and 2000, indicating recent selective pressures, possibly driven by industrialization, associated ... Clinical Signs. P. aeruginosa infections typically are contracted from heavily infested surfaces such as tubing or water tubs, and virtually any animal can ... Jul 12, 2018 ... P. aeruginosa is an opportunistic pathogen and it rarely affects healthy individuals. It can cause a wide range of infections, particularly in ...