What are the key messages about paracetamol safety that should be targeted to different age groups and populations?

N-acetylcysteine (NAC) is a safe and effective antidote which if used correctly prevents serious hepatic injury after paracetamol overdose. Sep 14, 2022 ... Survival rates from a paracetamol overdose are excellent, but only where medical treatment is sought within 2-6 hours after ingestion. If ... Sep 2, 2019 ... Paracetamol itself is not toxic, but in large amounts it overwhelms the body's ability to process it safely. This can lead to build up of a ... paracetamol overdose. Pablo Brenera,b, M.D., Mónica Ballardoa, M.D. ... Paracetamol overdose in a preterm neonate. Arch Dis Child Fetal Neonatal Ed. Aug 26, 2024 ... Acute poisoning: where a patient self-harms by taking a single large dose of paracetamol, or staggered overdose (several ingestions over greater ... Feb 23, 2018 ... Children aged under five years who are acutely unwell are particularly vulnerable to paracetamol toxicity, which can lead to liver failure and ... May 6, 2017 ... Paracetamol poisoning can occur if they ingest 75 mg per kilogram of body weight or more. Kidney and liver failure can occur from paracetamol poisoning. To characterise patients with paracetamol overdose, in terms of comorbidities, co-prescribed medications, prior paracetamol prescription, and incidence of short ... Dec 9, 2010 ... Paracetamol poisoning can result in lactic acidosis in two different scenarios. First, early in the course of poisoning and before the onset of hepatotoxicity. Symptoms of overdose; First aid for overdose; Paracetamol overdose; Treatment for drug overdose; Self-care after treatment with activated charcoal; Why an ...