What are the emerging issues and challenges in the field of paracetamol overdose that require further attention?

Paracetamol/Acetaminophen · Overdose = ingestion >75mg/kg. · >150mg/kg = Lethal. Special circumstances: Pregnancy – Toxic dose calculated using the patient's ... Aug 26, 2024 ... Acute poisoning: where a patient self-harms by taking a single large dose of paracetamol, or staggered overdose (several ingestions over greater ... To characterise patients with paracetamol overdose, in terms of comorbidities, co-prescribed medications, prior paracetamol prescription, and incidence of short ... Sep 30, 2017 ... Hence, the present work investigates the possible adverse effects of paracetamol on the rat brain. Our results show that an overdose treatment ... Sep 13, 2016 ... The impact factor for journals containing the top 100 cited paracetamol poisoning treatment articles ranged from 0.703 to 55.873. Twenty-eight ... Nov 18, 2024 ... This report describes a case of a child who was diagnosed with a paracetamol overdose that was associated with cortical blindness-complicated AL. Feb 24, 2022 ... The risk of oral paracetamol causing liver toxicity in adults with low bodyweight is recognised in the literature and in patient safety incident ... The SNAP (Scottish & Newcastle Acetylcysteine Protocol)-12 protocol is preferred over the classic 21-hour regimen for intravenous N-acetylcysteine (NAC) ... May 6, 2017 ... Paracetamol poisoning can occur if they ingest 75 mg per kilogram of body weight or more. Kidney and liver failure can occur from paracetamol poisoning. Dec 5, 2024 ... If not treated quickly, paracetamol overdoses can lead to severe outcomes, including liver failure, transplantation, or even death. N- ...