What are the arguments for and against limiting the quantity of paracetamol sold at one time?

N-acetylcysteine (NAC) is a safe and effective antidote which if used correctly prevents serious hepatic injury after paracetamol overdose. A rare intoxication due to a medical product occurring as a result of accidental or intentional overdosing of paracetamol (acetaminophen). Patients may develop ... Significant hepatotoxicity risk factors were male gender, alcohol abuse, an ingested paracetamol dose, and a timespan from ingestion to hospital admission. Comparing development of liver injury using the two versus three bag acetylcysteine regimen despite early treatment in paracetamol overdose. To characterise patients with paracetamol overdose, in terms of comorbidities, co-prescribed medications, prior paracetamol prescription, and incidence of short ... Dec 5, 2024 ... If not treated quickly, paracetamol overdoses can lead to severe outcomes, including liver failure, transplantation, or even death. N- ... Sep 11, 2019 ... Spot the signs of paracetamol poisoning · nausea · vomiting · lethargy · abdominal pain · seizures · coma and death. Call triple zero (000) ... The main toxicity following paracetamol poisoning is acute liver injury which results from the formation of a toxic metabolite of paracetamol. Paracetamol/Acetaminophen · Overdose = ingestion >75mg/kg. · >150mg/kg = Lethal. Special circumstances: Pregnancy – Toxic dose calculated using the patient's ... Jan 11, 2025 ... Paracetamol is still the almost exclusive cause of liver transplantation related to acute drug overdose, with an average of one case per six million ...