How can patient feedback be used to improve medication safety practices?

The main toxicity following paracetamol poisoning is acute liver injury which results from the formation of a toxic metabolite of paracetamol. This review explores recent estimates in rates of overdose and hepatotoxicity from paracetamol, including mechanism, diagnosis, and treatments. Dec 11, 2014 ... Intravenous acetylcysteine is the antidote to treat paracetamol overdose and is virtually 100% effective in preventing liver damage when given within 8 hours ... Paracetamol (acetaminophen) is a common means of self-poisoning in Europe and North America, often taken as an impulsive act of self-harm in young people. Jan 5, 2022 ... It is safe to use an ingested dose of > 150 mg/kg as the cut-off value for N-acetylcysteine treatment with risk stratification for hepatotoxicity. Sep 11, 2019 ... Spot the signs of paracetamol poisoning · nausea · vomiting · lethargy · abdominal pain · seizures · coma and death. Call triple zero (000) ... Oct 21, 2005 ... The majority ingested more than 10 g of paracetamol. It is thought that paracetamol hepatotoxicity occurs only when >125 mg/kg is absorbed. Paracetamol poisoning, also known as acetaminophen poisoning, is caused by excessive use of the medication paracetamol (acetaminophen). ... Most people have few ... Nov 8, 2019 ... Although health professionals may assume that patients know how to use paracetamol, overdose rates continue to rise. May 2, 2022 ... Paracetamol Levels · If the level is below 1000 µmol/L at 2 hours then it is safe to discharge the child with no treatment. · If the level is ...