How can aftercare programs address both the physical and psychological consequences of overdose?

Acetaminophen (N-acetyl-para-aminophenol, paracetamol, APAP) toxicity is common primarily because the medication is so readily available, and there is a ... NOTE: This protocol differs from advice on TOXBASE, however the general paracetamol overdose guidance still applies. Please ensure the EDLs/IDLs are given a ... ... paracetamol overdose. Serum levels of digoxin-like immunoreactive substances were significantly increased in both viral hepatitis and paracetamol overdose ... *Ingested paracetamol = <75mg/kg. Ingested paracetamol = ≥75mg/kg. *Clinical judgement required. • If doubt then assume ≥150mg/kg. Take bloods. No blood tests. Nov 2, 2022 ... Information for patients attending the Emergency Department following a paracetamol overdose. Download and print as a PDF (88kB pdf) Acute Management · >200 mg/kg (or 10 g) ingested over a 24 hour period · >150 mg/kg/day (or 6 g) ingested over a 48 hour period · >100 mg/kg/day ingested over a ... Apr 18, 2018 ... A new in silico paracetamol toxicity identification framework is described to simulate the PK/PD behavior of paracetamol and a panel of corresponding toxicity ... Aladote®- treatment of paracetamol/acetaminophen overdosing. Aladote® is a “first-in-class” drug candidate with the potential to prevent the risk of liver ... Feb 2, 2024 ... Signs and symptoms · 18-72 h after ingestion · Patients develop right upper quadrant abdominal pain, anorexia, nausea, and vomiting · Right upper ... Paracetamol/Acetaminophen · Overdose = ingestion >75mg/kg. · >150mg/kg = Lethal. Special circumstances: Pregnancy – Toxic dose calculated using the patient's ...